Accepted manuscript
Environmental epigenetics and phytoestrogen/phytochemical exposures
The Journal of steroid biochemistry and molecular biology, Vol.139, pp.270-276
01/2014
Handle:
https://hdl.handle.net/2376/109246
PMCID: PMC3644519
PMID: 23274117
Abstract
One of the most important environmental factors to promote epigenetic alterations in an individual is nutrition and exposure to plant compounds. Phytoestrogens and other phytochemicals have dramatic effects on cellular signaling events, so have the capacity to dramatically alter developmental and physiological events. Epigenetics provides one of the more critical molecular mechanisms for environmental factors such as phytoestrogens/phytochemicals to influence biology. In the event these epigenetic mechanisms become heritable through epigenetic transgenerational mechanisms the impacts on the health of future generations and areas such as evolutionary biology need to be considered. The current review focuses on available information on the environmental epigenetics of phytoestrogen/phytochemical exposures, with impacts on health, disease and evolutionary biology considered. This article is part of a Special Issue entitled 'Phytoestrogens'.
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Details
- Title
- Environmental epigenetics and phytoestrogen/phytochemical exposures
- Creators
- Carlos M Guerrero-Bosagna - Center for Reproductive Biology, School of Biological Sciences, Washington State University, Pullman, WA 99164-4236, USAMichael K Skinner
- Publication Details
- The Journal of steroid biochemistry and molecular biology, Vol.139, pp.270-276
- Academic Unit
- Biological Sciences, School of
- Publisher
- Elsevier; England
- Number of pages
- 7
- Grant note
- R01 ES012974 / NIEHS NIH HHS
- Identifiers
- 99900547132201842
- Language
- English
- Resource Type
- Accepted manuscript