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Definition of Epigenetic Transgenerational Inheritance and Biological Impacts
Book chapter

Definition of Epigenetic Transgenerational Inheritance and Biological Impacts

Eric Nilsson and Michael K. Skinner
Transgenerational Epigenetics, pp.11-16
Elsevier Inc
2014

Abstract

Disease etiology Environmental exposures Epimutations Germline Non-genetic inheritance Transgenerational Epigenetics Evolutionary Biology
A review of the environmentally induced epigenetic transgenerational inheritance phenomenon is presented. The term transgenerational is defined to clarify the distinction with direct exposure toxicity. The concept of germline epimutations mediating a transgenerational phenotype is discussed. The potential impact of environmentally induced epigenetic transgenerational inheritance on our understanding of disease etiology and evolutionary biology molecular mechanisms is reviewed

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