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Environmental Epigenetics and Epigenetic Transgenerational Inheritance
Book chapter

Environmental Epigenetics and Epigenetic Transgenerational Inheritance

Michael K. Skinner
Environmental Epigenomics in Health and Disease, pp.245-256
Epigenetics and Human Health, Springer Berlin Heidelberg
01/01/2013

Abstract

Developmental origin of disease Germline Inheritance Toxicants Transgenerational Epigenetics
The developing role of environmental epigenetics in biology and medicine is discussed in relationship to its impact on transgenerational inheritance. The ability of environmental factors, such as nutrition and toxicants, to promote transgenerational adult-onset disease through alterations in the germline epigenome is reviewed. Observations suggest epigenetic transgenerational inheritance has a significant impact on evolutionary biology, disease etiology, and toxicology.

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