Book chapter
Regulating Nanozymes for Bioanalysis
Biomedical Nanozymes, pp.15-44
Springer Nature Singapore
10/04/2023
Abstract
Nanozymes with enzyme-like activity can perform catalytic reactions like enzymes. Nanozymes have been extensively used in biosensing, biomedicine, and other fields owing to their high stability, low cost, and various functions. Specifically, nanozymes that exhibit superior enzyme-like activity and specific physicochemical properties have progressively become outstanding alternatives to enzymes for bioanalysis. To better adapt to bioanalytical applications, many strategies have been developed for tuning the catalytic activity of nanozymes and designing biosensing platforms for advanced bioanalysis. In this chapter, the most recent developments in emerging bioanalysis based on nanozymes are summarized. First, the classification and the catalytic mechanisms of nanozymes are provided. Then, the regulation of the catalytic activity and specificity of nanozymes is discussed in detail, which is closely related to the sensitivity and accuracy of bioanalysis. Great accomplishments in bioanalysis towards different targets, including ions, small biomolecules, nucleic acids, proteins, and cells, are highlighted by utilizing nanozyme-based catalytic signal amplification. Finally, the challenges and potential applications of nanozymes in bioanalysis are discussed.
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Details
- Title
- Regulating Nanozymes for Bioanalysis
- Creators
- Yuexi Fan - Central China Normal UniversityYinjun Tang - Central China Normal UniversityWeiqing Xu - Central China Normal UniversityYu Wu - Central China Normal UniversityWenling Gu - Central China Normal UniversityDan Du - Washington State UniversityYuehe Lin - Washington State UniversityChengzhou Zhu - Central China Normal University
- Contributors
- Hui Wei (Editor)Genxi Li (Editor)Jinghong Li (Editor)
- Publication Details
- Biomedical Nanozymes, pp.15-44
- Academic Unit
- School of Mechanical and Materials Engineering
- Publisher
- Springer Nature Singapore; Singapore
- Number of pages
- 30
- Identifiers
- 99901227640901842
- Language
- English
- Resource Type
- Book chapter