Book chapter
Semen Analysis: Assaying Sperm Epigenetics
Encyclopedia of Reproduction, pp.117-123
Elsevier Inc, Second Edition
2018
Abstract
The mammalian sperm contains a very specialized and singular epigenetic landscape that is essential for biology and fertility. DNA methylation, spermatozoal RNAs and nuclear protein composition are marks thought to be remnants of epigenetic transitions occurring during spermatogenesis. This unique nature of sperm epigenome has led some labs to begin to study the links between sperm epigenetic marks and various forms of infertility. This article will focus on the different techniques used in the context of sperm epigenetics and their potential diagnostic utilization in male infertility and pregnancy outcomes.
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Details
- Title
- Semen Analysis: Assaying Sperm Epigenetics
- Creators
- Millissia Ben Maamar - Washington State UniversityIngrid Sadler-RigglemanMichael K. Skinner - Washington State University
- Publication Details
- Encyclopedia of Reproduction, pp.117-123
- Academic Unit
- Biological Sciences, School of
- Publisher
- Elsevier Inc
- Edition
- Second Edition
- Identifiers
- 99901080819401842
- Language
- English
- Resource Type
- Book chapter