Review
Deciphering gene expression regulatory networks
Current Opinion in Genetics & Development, Vol.12(2), pp.130-136
2002
Handle:
https://hdl.handle.net/2376/110531
PMID: 11893484
Abstract
In the past year, great strides have been made in our understanding of the regulatory networks that control gene expression in the model eukaryote
Saccharomyces cerevisiae. The development and use of a number of genomic tools, including genome-wide location and expression analysis, has fueled this progress. In addition, a variety of computational algorithms have been devised to mine genomic sequence for conserved regulatory motifs in co-regulated genes. The recent description of the genetic network controlling the cell cycle illustrates the tremendous potential of these approaches for deciphering gene expression regulatory networks in eukaryotic cells.
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Details
- Title
- Deciphering gene expression regulatory networks
- Creators
- John J Wyrick - Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USARichard A Young - Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA
- Publication Details
- Current Opinion in Genetics & Development, Vol.12(2), pp.130-136
- Academic Unit
- Molecular Biosciences, School of
- Publisher
- Elsevier Ltd
- Identifiers
- 99900547476301842
- Language
- English
- Resource Type
- Review