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Temperature-regulated expression of bacterial virulence genes
Review   Peer reviewed

Temperature-regulated expression of bacterial virulence genes

Michael E Konkel and Kit Tilly
Microbes and Infection, Vol.2(2), pp.157-166
2000
Handle:
https://hdl.handle.net/2376/108599
PMID: 10742688

Abstract

virulence temperature gene regulation
Virulence gene expression in most bacteria is a highly regulated phenomenon, affected by a variety of parameters including osmolarity, pH, ion concentration, iron levels, growth phase, and population density. Virulence genes are also regulated by temperature, which acts as an `on-off' switch in a manner distinct from the more general heat-shock response. Here, we review temperature-responsive expression of virulence genes in four diverse pathogens.

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