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Rights Statements InC/1.0 , Open Access
Conference poster
Evaluation of ion mobility mass spectrometry (IMMS) for determining the isomeric heterogeneity of bovine submaxillary mucin (BSM)
Washington State University Academic Showcase (Pullman, Washington, 03/30/2012)
03/30/2012
Handle:
https://hdl.handle.net/2376/3875
Abstract
Rapid separation and analysis of isomeric species are essential steps in the analytical protocol of carbohydrate structure analysis for glycomics research. This study evaluated the use of ion mobility spectrometry (IMS) prior to MS as an additional rapid isomer separation step prior to mass spectral analysis. Neutral oligosaccharide alditols of BSM were investigated in positive mode. Multiple isomers were detected for specific m/z on millisecond time scale, which would be difficult or impossible using MS alone or single LC column. Tandem MS provide valuable information for elucidating glycan structures and understanding the isomeric nature of glycans.
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Details
- Title
- Evaluation of ion mobility mass spectrometry (IMMS) for determining the isomeric heterogeneity of bovine submaxillary mucin (BSM)
- Creators
- Hongli Li (Author)Brad Bendiak (Author)Kimberly Kaplan (Author)William Siems (Author)Herbert H. Jr. Hill (Author)
- Conference
- Washington State University Academic Showcase (Pullman, Washington, 03/30/2012)
- Academic Unit
- WSU Academic Showcase 2012
- Grant note
- Funding agency: NIH (National Institute of Health). Washington State University, Pullman, WA
- Identifiers
- 99900502298501842
- Copyright
- In copyright ; openAccess ; http://rightsstatements.org/vocab/InC/1.0/ ; http://purl.org/eprint/accessRights/OpenAccess
- Language
- English
- Resource Type
- Conference poster