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MONOLIGNOL AND LIGNAN BIOSYNTHETIC STUDIES: FROM REACTION MECHANISMS TO NEXT GENERATION SEQUENCING
Dissertation   Open access

MONOLIGNOL AND LIGNAN BIOSYNTHETIC STUDIES: FROM REACTION MECHANISMS TO NEXT GENERATION SEQUENCING

CHOONSEOK LEE
Doctor of Philosophy (PhD), Washington State University
01/2012
Handle:
https://hdl.handle.net/2376/4629
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Abstract

Three objectives were studied: determination of the biochemical mechanisms of an Arabidopsis thaliana allylic double bond reductase (AtDBR1) producing stress/defense metabolites, dihydrocinnamyl aldehydes, and the Arabidopsis cinnamyl alcohol dehydrogenase (AtCAD5), as well as exploring the potential of utilizing next-generation sequencing to help identify unknown biochemical steps in formation of the lignan, podophyllotoxin, in Podophyllum species.

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