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Unraveling the regulation of mint monoterpene biosynthesis: Development and experimental testing of kinetic mathematical models
Dissertation   Open access

Unraveling the regulation of mint monoterpene biosynthesis: Development and experimental testing of kinetic mathematical models

Rigoberto Rios-Estepa
Washington State University
Doctor of Philosophy (PhD), Washington State University
12/2008
DOI:
https://doi.org/10.7273/000005835
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Abstract

Peppermint
In this dissertation a combination of mathematical modeling and experimental testing was used to study the regulation of monoterpene metabolism in peppermint. Due to the regulatory complexity and compartmentalization of plant metabolism, it is essential to understand which modeling approach is suitable to tackle a specific scientific problem. Thus, a comprehensive review which summarizes pros and cons of the various modeling approaches is included as the second chapter of this dissertation. For dynamic experimental systems, kinetic modeling is the most reliable strategy, since it accounts for the continuous diurnal, circadian and seasonal changes in the expression and activities of biosynthetic enzymes.

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