Encyclopedia entry
Testis Cell and Organ Culture
Encyclopedia of Reproduction, pp.161-164
Elsevier Inc, Second Edition
2018
Abstract
The testis, the male gonad in animals, produces male germ cells and sexual hormones. It contains several primary cell types. Germ cells, Sertoli cells and peritubular cells are located within the seminiferous tubules. Germ cells are developed in the tubules supported by the two types of somatic cells, Sertoli and peritubular cells. In between tubules (interstitium) Leydig cells are present. Leydig cells are the location of steroidogenesis and synthesize hormones essential for germ cell differentiation. Different approaches to isolating and culturing testis cell types, and to performing organ culture on testis fragments, are reviewed. Cell culture and co-culture of individual cell populations from the testis as well as organ culture involving testis tissue has advanced the understanding of the processes of spermatogenesis, the interactions of specific cell types (signal transduction), and mechanisms of steroidal hormone actions.
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Details
- Title
- Testis Cell and Organ Culture
- Creators
- Ingrid Sadler-RigglemanMichael K. Skinner - Washington State University
- Publication Details
- Encyclopedia of Reproduction, pp.161-164
- Academic Unit
- Biological Sciences, School of
- Publisher
- Elsevier Inc
- Edition
- Second Edition
- Identifiers
- 99901080818901842
- Language
- English
- Resource Type
- Encyclopedia entry