Essay
Assessment of resistance to antibiotics in pseudomonas syringae pv. syringae phytotoxin secretion mutants
09/2000
Handle:
https://hdl.handle.net/2376/2548
Abstract
Pseudomonas syringae pv. syringae is a well-known bacterial plant pathogen of many agronomically important crops such as sweet cherry, beans, and corn (2). P. s. pv. syringae produces two necrosis inducing phytotoxins: syringomycin (syr) and syringopeptin (syp). These phytotoxins are virulence factors that extensively contribute to the pathogen's ability to cause disease (9). The genes responsible for syringomycin and syringopeptin production are clustered on the bacterial chromosome and include genes coding for biosynthesis, regulation, and secretion of both syringomycin and syringopeptin (10). Interestingly, genes were identified that code for two complete secretion systems. Mutations in these genes result in the reduction or inability of P. s. pv. syringae to secrete syringomycin or syringopeptin (11). Secretion is the transportation of products such as toxins, metabolic waste products, or antibiotics out of a cel!. Secretion is thought to occur for two reasons: prevent toxic levels of substances from accumulating in the cell and give the bacterium a competitive advantage by releasing toxins into the environment. It is hypothesized that the mechanisms of secretion in P. s. pv. syringae are similar to those of related bacteria of medical importance such as Pseudomonas aeruginosa (13). Most bacterial plant pathogens have one or more of four secretory pathways that utilize a combination of proteins to form transporters that work in the cytoplasm, inner membrane, and outer membrane (9).
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Details
- Title
- Assessment of resistance to antibiotics in pseudomonas syringae pv. syringae phytotoxin secretion mutants
- Creators
- Renee L. Schaeffer (Author)
- Academic Unit
- Honors Theses (WSU Pullman, Passed with Distinction)
- Identifiers
- 99900590546201842
- Copyright
- http://rightsstatements.org/vocab/InC/1.0/; http://www.ndltd.org/standards/metadata; http://purl.org/eprint/accessRights/OpenAccess; In copyright; Publicly accessible; openAccess
- Language
- English
- Resource Type
- Essay