Essay
Ovarian hormone modulation of supraspinal THC-Induced analgesia
2013
Handle:
https://hdl.handle.net/2376/4364
Abstract
For my thesis, I wanted to determine which female hormone -- estradiol, progesterone, or both, was responsible for females’ increased THC sensitivity. I approached this question by removing the internal source of these hormones, the ovaries, from female rats, and then putting them on a hormone injection regimen to mimic their natural reproductive cycle. I also wanted to examine brain THC sensitivity, because there was evidence that hormones modulate THC’s effect by causing fluctuations in the sites to which THC binds in the brain. Therefore, THC was administered directly into the brain.
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Details
- Title
- Ovarian hormone modulation of supraspinal THC-Induced analgesia
- Creators
- Alisha Mcbride (Author)
- Contributors
- Rebecca Craft (Advisor)
- Academic Unit
- Honors Theses (WSU Pullman, Passed with Distinction)
- Identifiers
- 99900590749801842
- Copyright
- http://rightsstatements.org/vocab/InC/1.0/; http://www.ndltd.org/standards/metadata; http://purl.org/eprint/accessRights/OpenAccess; In copyright; Publicly accessible; openAccess
- Language
- English
- Resource Type
- Essay