Essay
Selective derivation of protein carboxylate esters: Development of a new detection and quantification method
2004
Handle:
https://hdl.handle.net/2376/2466
Abstract
Post-translational modifications of a protein can affect the structural stability or biological activity of a protein. One such modification is the esterification of protein carboxylic acids. Formation of protein carboxylate esters is involved in protein damage repair and signaling transduction. Current methods for detecting protein carboxylate esters are cumbersome and only semi-quantitative. The ability to detect and quantify these modifications using a proteomics approach is an important step to aid in further study of these modifications. Here we show a method being developed for facile detection and precise quantification of protein carboxylate esters.
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Details
- Title
- Selective derivation of protein carboxylate esters: Development of a new detection and quantification method
- Creators
- Laura A. Gillies (Author)
- Contributors
- Zhouhui Sunny Zhou (Advisor)
- Academic Unit
- Honors Theses (WSU Pullman, Passed with Distinction)
- Identifiers
- 99900590745101842
- Copyright
- http://rightsstatements.org/vocab/InC/1.0/; http://www.ndltd.org/standards/metadata; http://purl.org/eprint/accessRights/OpenAccess; In copyright; Publicly accessible; openAccess
- Language
- English
- Resource Type
- Essay