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CCBY-NCSA_V3.0_US, Open Access
Thesis
A Comparison Between the Effects of 0.025% and 0.075% Capsaicin on Painful Diabetic Neuropathy
Washington State University
Master of Nursing (MN), Washington State University
05/1996
Handle:
https://hdl.handle.net/2376/3927
Abstract
The purpose of this study was to determine the difference between two different strengths of topical capsaicin cream on relieving the pain associated with diabetic neuropathy. This quasi-experimental single blind and randomized drug study evaluated 15 diabetics with painful peripheral neuropathy during treatment with 0.025% or 0.075% capsaicin. Neuropathy pain was assessed at baseline and at weeks 1, 3, 5, 7 and 8 by a vertical 1OOmm visual analog scale in which participants rated their most intense pain. Repeated measures analysis of variance showed no significant difference between the two available over-the-counter strengths of capsaicin (p=0.496) in relieving the pain associated with diabetic neuropathy. However, analysis of variance showed significant pain relief over time for both groups (p=O.OOO). Compliance with the study's treatment was evaluated by t-tests (t=0.520, df=1, p=0.612), and Pearson chi-square (x2=3.951, df=5, p=0.557) methods, which showed no significant difference between the two groups. The study concluded that capsaicin's 0.025% regular strength cream is as effective as the 0.075% extra-strength in relieving diabetic neuropathy pain.
Metrics
Details
- Title
- A Comparison Between the Effects of 0.025% and 0.075% Capsaicin on Painful Diabetic Neuropathy
- Creators
- Mercedes Gonzalez-Aller Solis
- Contributors
- Lorna Schumann (Advisor)
- Awarding Institution
- Washington State University
- Academic Unit
- Research Projects, College of Nursing
- Theses and Dissertations
- Master of Nursing (MN), Washington State University
- Publisher
- Washington State University; Spokane, Washington
- Identifiers
- 99900590731001842
- Copyright
- http://creativecommons.org/licenses/by-nc-sa/3.0/us; Creative Commons Attribution-NonCommercial-ShareAlike 3.0 United States (CC BY-NC-SA 3.0 US)
- Language
- English
- Resource Type
- Thesis