Thesis
A comparison of the effect of three different low-level laser power settings on limb function, bone healing and pain in dogs following tibial plateau levelling osteotomy: a pilot stude
Washington State University
Master of Science (MS), Washington State University
08/2020
DOI:
https://doi.org/10.7273/000000088
Handle:
https://hdl.handle.net/2376/119181
Abstract
Objective: To evaluate the effect of different low-level laser therapy (LLLT) power settings on
pain, limb use, bone healing, and the synovial prostaglandin E2 (PGE2) concentrations in dogs
after tibial plateau levelling osteotomy (TPLO) surgery.
Materials and Methods: A randomized, double-blinded, prospective study with 9 client-owned
dogs with spontaneous unilateral cranial cruciate ligament rupture. Patients were divided into 3
LLLT power treatment groups; 2, 4 or 6 J/cm2
, respectively, using two 808nm, 500mW power
Class IIIb laser sources. All dogs underwent stifle arthroscopy followed by TPLO surgery.
Outcome metrics included serial orthopaedic examinations, accelerometery, goniometry, ground
reaction force analysis (GRF), Canine Brief Pain Inventory (CBPI), Modified Glasgow
Composite Pain Scale (MGPS), radiographic scoring, and synovial PGE2 concentrations over the
8-week study period.
Results: There were no significant differences in outcome metrics between all treatment groups
over the study period. Positive trends were noted with CBPI, MGPS, and GRF in 2 J/cm2
and 6 J/cm2
groups and increased bone healing and decreased synovial PGE2 concentrations in the 4
J/cm2
group.
Clinical Significance: Although statistical significance was not detected in this study, trends
were observed between the 3 laser treatment groups. The statistical variables from this pilot
study will aid in designing a larger controlled, LLLT power-variable study in future TPLO
surgery patients.
Metrics
Details
- Title
- A comparison of the effect of three different low-level laser power settings on limb function, bone healing and pain in dogs following tibial plateau levelling osteotomy: a pilot stude
- Creators
- Chi-Ya Chen
- Contributors
- PETER J GILBERT (Degree Supervisor) - Washington State University, Veterinary Clinical Sciences, Department ofSTEVEN A MARTINEZ (Committee Member) - Washington State University, Veterinary Clinical Sciences, Department ofTINA JO OWEN (Committee Member) - Washington State University, Veterinary Clinical Sciences, Department ofJESSICA A BUNCH (Committee Member) - Washington State University, Veterinary Clinical Sciences, Department of
- Awarding Institution
- Washington State University
- Academic Unit
- Veterinary Medicine, College of
- Theses and Dissertations
- Master of Science (MS), Washington State University
- Publisher
- Washington State University
- Format
- pdf
- Number of pages
- 41
- Identifiers
- 99900591863601842
- Language
- English
- Resource Type
- Thesis