Thesis
Comparison of enterprise point of care (EPOC) and Nova CCX analyzers for determination of arterial PH, blood gas, and electrolyte values in dog and horse blood
Washington State University
Master of Science (MS), Washington State University
2016
Handle:
https://hdl.handle.net/2376/100571
Abstract
Objectives: To evaluate 1) the precision of a portable blood gas analyzer, the Enterprise Point of Care (EPOC), using dog blood and 2) the agreement between the EPOC and central laboratory analyzer Nova critical care express (Nova CCX) for the assessment of arterial pH, blood gases and electrolyte parameters in dog and horse blood. Design: Experimental prospective study. Animals/ Samples: 46 dog samples and 75 horse samples. Procedures: Whole arterial blood samples were drawn from dogs and horses. The analyses were performed on the EPOC and Nova analyzers to determine pH, partial pressure of arterial carbon dioxide (PaCO2), partial pressure of arterial oxygen (PaO2), and hematocrit (Hct), sodium (Na+), potassium (K-), and chloride (Cl-). The comparison of the results from the same sample analyzed twice on the EPOC unit was used for the precision study, whereas the comparison of results from the same sample analyzed by both the EPOC and Nova analyzers was used for the agreement study. Statistical comparisons were made using the coefficient of variation (CV%) for the precision study and linear regression, Pearson correlation, and Bland-Altman plot for the agreement study. Results: The EPOC analysis offered good precision in measurements of dog arterial blood pH and blood gases. For the agreement study using both dog and horse blood, regression and correlation values were above 0.93 for arterial pH and blood gases, but lower for sodium and chloride. Bland-Altman plots demonstrated agreement between the two analyzers in measuring all blood gases and electrolytes, except for PaCO2 and Cl-. Clinical implications: The EPOC analyzer is useful for blood analysis of anesthetized dogs and horses and the results compare well with the Nova analyzer. Because of its portability, the EPOC offers the fastest test results, enabling faster diagnosis and treatment decisions.
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Details
- Title
- Comparison of enterprise point of care (EPOC) and Nova CCX analyzers for determination of arterial PH, blood gas, and electrolyte values in dog and horse blood
- Creators
- Taher Naser Elmeshreghi
- Contributors
- Stephen A. Greene (Degree Supervisor)
- Awarding Institution
- Washington State University
- Academic Unit
- Veterinary Medicine, College of
- Theses and Dissertations
- Master of Science (MS), Washington State University
- Publisher
- Washington State University; [Pullman, Washington] :
- Identifiers
- 99900524806201842
- Language
- English
- Resource Type
- Thesis