Interstitial cystitis/painful bladder disorder is an uncomfortable disease for which there is no known cause and no consistently effective treatment. Many research studies purport subjective symptom relief with dietary restriction of certain food metabolites (Gillespie, 1993; Koziol, 1994; Theoharides, 1994). Gillespie (1993) demonstrated improvement of serum histamine and ammonia levels, as well as urine indicans, xanthurenic and kynurenic acid levels with restriction of arylalkylamines and acidic foods. The purpose of this quasi-experimental study with a counter balance design was to determine the effect of withholding acidic or arylalkylamine food metabolites on the symptoms of interstitial cystitis/painful bladder disorder. The study also evaluated symptom relief when arylalkylamines plus acidic foods and fluids were withheld. There was no statistical significance in the response to the dietary restrictions. The clinical significance was a reduction in the daily symptom level that was also statistically significant and reduced voidings per day.
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Details
Title
Effect of Food Component Restrictions on Symptoms of Interstitial Cystitis/Painful Bladder Disorder
Creators
Susan V. Small
Contributors
Lorna Schumann (Advisor)
Awarding Institution
Washington State University
Academic Unit
Research Projects, College of Nursing
Theses and Dissertations
Master of Nursing (MN), Washington State University
Publisher
Washington State University; Spokane, Washington
Identifiers
99900590731301842
Copyright
http://creativecommons.org/licenses/by-nc-sa/3.0/us; Creative Commons Attribution-NonCommercial-ShareAlike 3.0 United States (CC BY-NC-SA 3.0 US)