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CCBY-NCSA_V3.0_US, Open Access
Thesis
Fibromyalgia Syndrome: Pathophysiology, Diagnosis and Interventions
Washington State University
Master of Nursing (MN), Washington State University
04/2001
Handle:
https://hdl.handle.net/2376/3930
Abstract
Fibromyalgia (FM) is a non-inflammatory pain syndrome characterized by generalized myalgia and localized point tenderness. Associated symptoms typically include sleep disturbance, fatigue, anxiety, morning stiffness, and depression. The incidence of fibromyalgia is estimated to be 2% in the general community and is increasing among perimenopausal and menopausal women. The etiology of fibromyalgia is not known. More recent research has focused on neuroendocrine and central nervous system involvement. Proposed etiologies include: primary adrenal insufficiency as a result of an altered hypothalamic-pituitary-adrenal (HPA) axis; altered regulation of the sympathetic nervous system; hypoactive corticotropin-releasing hormone (CRR) neuron; and changes in the central processing of pain at the spinal level. The diagnosis of fibromyalgia is difficult to make because of symptom variability and the coexistence of other conditions with fibromyalgia. The unknown etiology and pathogenesis make fibromyalgia difficult to treat. Antidepressants in combination with exercise appear to be the most effective therapy. The management goals for fibromyalgia are to control depression, improve sleep disturbance, and reduce pain.
Metrics
Details
- Title
- Fibromyalgia Syndrome: Pathophysiology, Diagnosis and Interventions
- Creators
- Stacey K. Wright
- Contributors
- Lorna Schumann (Advisor)
- Awarding Institution
- Washington State University
- Academic Unit
- Research Projects, College of Nursing
- Theses and Dissertations
- Master of Nursing (MN), Washington State University
- Publisher
- Washington State University; Spokane, Washington
- Identifiers
- 99900590730801842
- Copyright
- http://creativecommons.org/licenses/by-nc-sa/3.0/us; Creative Commons Attribution-NonCommercial-ShareAlike 3.0 United States (CC BY-NC-SA 3.0 US)
- Language
- English
- Resource Type
- Thesis