Thesis
Glutamic acid valorization through solvent-enabled decarboxylation for 2-pyrrolidone production
Washington State University
Master of Science (MS), Washington State University
12/2020
DOI:
https://doi.org/10.7273/000004249
Handle:
https://hdl.handle.net/2376/125148
Abstract
With the annual global food waste volume accumulating dramatically, the demand for a sustainable treatment is ever-growing. Glutamic acid is the most abundant amino acid component in protein-rich food waste biomass and the largest scale-produced amino acid worldwide. Therefore, its valorization has become more and more important and attractive. Herein, a state-of-the-art solvent-enabled decarboxylative conversion of L-glutamic acid into 2-pyrrolidone was proposed. The effect of different solvents, including pure water and a series of organic solvents, on the reaction pathways for L-glutamic acid was elucidated. 100 % yield of 2-pyrrolidone was successfully achieved in acetone solvent under optimized reaction condition (i.e., 200 ℃, 20 bar of N2, 30 min), with the highlight of the negative impact of residual water in acetone on this decarboxylative conversion. Surprisingly, 2-pyrrolidone was found to have an autocatalytic effect on the decarboxylation of L-glutamic acid and L-pyroglutamic acid to different extent, enhancing the reaction efficiency on the whole. This solvent-enabled decarboxylative conversion reduces the cost for noble metal catalysts, avoids harsh reaction conditions and thus paves the way for scaled-up industrial production of 2-pyrrolidone from L-glutamic acid.
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Details
- Title
- Glutamic acid valorization through solvent-enabled decarboxylation for 2-pyrrolidone production
- Creators
- Ziling Wang
- Contributors
- Meijun Zhu (Advisor) - Washington State University, Food Science, School of
- Awarding Institution
- Washington State University
- Academic Unit
- Food Science, School of
- Theses and Dissertations
- Master of Science (MS), Washington State University
- Publisher
- Washington State University
- Identifiers
- 99900896418201842
- Language
- English
- Resource Type
- Thesis