Thesis
Intra-Articular Corticosteroids: An Investigation of Uses, Benefits, and Risks
Washington State University
Master of Nursing (MN), Washington State University
05/1999
Handle:
https://hdl.handle.net/2376/4030
Abstract
Injectible corticosteroids have been investigated as a treatment of musculoskeletal pain since\nbefore the 1950's (Hench, Kendall, Slocumb, & Polley, 1949). Intra-articular administration affords patients varying levels and periods of symptom relief. Duration and extent of relief are influenced by length of symptomatology and frequency of recurrence. Untoward effects may be experienced either locally, systemically, or even allergic in nature (Alexiou, Kau, Luppa, & Arnold, 1998; Downs, Lear, & Kennedy, 1998). Glucocorticoids, a class of naturally occurring corticosteroids, are important in the body's management of carbohydrates, proteins, fats, blood pressure, sodium and potassium balance, and most importantly, the reduction of inflammation. Many are synthetically manufactured for a variety of uses (Mosby's Medical, Nursing, and Allied Health Dictionary, 1994). The purpose of this paper is to review advantages of intra-articular use including appropriate protocols and to identify the specific side effects with their risk of occurrence. Although many have studied intra-articular corticosteroid use (presenting a range of variables and methods of study), standards for dosing volumes and concentrations, and for measuring disability, pain and status changes have not been established. Therefore, comparison among studies is difficult. Effects and outcomes have not been investigated in a manner that allows risks and benefits to be consistently determined.
Metrics
Details
- Title
- Intra-Articular Corticosteroids: An Investigation of Uses, Benefits, and Risks
- Creators
- Kathi M. Stevens
- Contributors
- Renee Hoeksel (Advisor)
- Awarding Institution
- Washington State University
- Academic Unit
- Research Projects, College of Nursing
- Theses and Dissertations
- Master of Nursing (MN), Washington State University
- Publisher
- Washington State University; Spokane, Washington
- Identifiers
- 99900590727301842
- Copyright
- http://creativecommons.org/licenses/by-nc-sa/3.0/us; Creative Commons Attribution-NonCommercial-ShareAlike 3.0 United States (CC BY-NC-SA 3.0 US)
- Language
- English
- Resource Type
- Thesis