Thesis
Mechanism of pathogen entry into tick cells
Washington State University
Master of Science (MS), Washington State University
2019
Handle:
https://hdl.handle.net/2376/102819
Abstract
Many tick-borne diseases are caused by intracellular bacterial pathogens. Methods to prevent these diseases in humans and animals rely on preventing tick exposure and are partially effective and difficult to implement. For successful transmission, these pathogens must enter tick cells, the mechanism of which is entirely unknown. Understanding these mechanisms of entry may lead to widely applicable methods to prevent tick-borne diseases. Using Francisella novicida, which colonizes and is transmitted by Dermacentor andersoni ticks, we are determining if pathogen entry into tick cells is receptor-mediated or occurs via macropinocytosis.
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Details
- Title
- Mechanism of pathogen entry into tick cells
- Creators
- Hanen Baggar
- Contributors
- Susan M. Noh (Degree Supervisor)
- Awarding Institution
- Washington State University
- Academic Unit
- Veterinary Medicine, College of
- Theses and Dissertations
- Master of Science (MS), Washington State University
- Publisher
- Washington State University; [Pullman, Washington] :
- Identifiers
- 99900525168901842
- Language
- English
- Resource Type
- Thesis