Thesis
Phonological working memory on a nonword repetition task in individuals with galactosemia
Washington State University
Master of Arts (MA), Washington State University
2011
Handle:
https://hdl.handle.net/2376/100119
Abstract
Classic galactosemia is a recessive inborn error of metabolism that results in speech or language disorders in 60-80% of affected individuals. Nonword repetition tasks have been used extensively to assess phonological working memory of individuals with language impairments. The repetition of nonwords has been proposed to be relatively independent of level of cognitive function. A nonword repetition task (NRT) was used to determine whether individuals with galactosemia (IWG) differ from healthy controls (HC) in phonological working memory. A relation between performance on the NRT and full-scale IQ (FSIQ) scores in IWG was assessed. Finally, evidence for neurodegeneration in phonological working memory across ages of IWG was investigated. Method The NRT was administered to 162 children aged 4;0-16;11 and 43 adults aged 17;0- 69;11. Thirty-two of the children and 33 adults had been diagnosed with galactosemia. All participants were administered the Goldman-Fristoe Test of Articulation-2 (GFTA-2). In addition, the galactosemia group was administered the Peabody Picture Vocabulary Test-4 (PPVT-4), the Oral and Written Language Scale (OWLS) and a full scale IQ (FSIQ) test. Results: Results indicated significantly lower scores on the NRT for IWG than for HC groups. Relationships were found among NRT scores and FSIQ, increasing age, articulation, and receptive language, and the presence of childhood apraxia of speech (CAS). Discussion IWG have deficits in phonological working memory compared to HC as measured by performance on the NRT. Performance on the NRT provided no evidence of neurodegeneration with increasing age for IWG.
Metrics
Details
- Title
- Phonological working memory on a nonword repetition task in individuals with galactosemia
- Creators
- Tonia Michelle Duggins
- Contributors
- Nancy L. Potter (Degree Supervisor)
- Awarding Institution
- Washington State University
- Academic Unit
- Sociology, Department of
- Theses and Dissertations
- Master of Arts (MA), Washington State University
- Publisher
- Washington State University; Pullman, Wash. :
- Identifiers
- 99900525198601842
- Language
- English
- Resource Type
- Thesis