Thesis
Prevalence and factors associated with initial and subsequent shockable cardiac arrest rhythms and their association with patient outcomes in dogs and cats undergoing cardiopulmonary resuscitation: a Recover registry study
Washington State University
Master of Science (MS), Washington State University
2023
DOI:
https://doi.org/10.7273/000005302
Abstract
The objective of this study was to report the prevalence of initial shockable cardiac arrest rhythms (I-SHKR), incidence of subsequent shockable cardiac arrest rhythms (S-SHKR), factors associated with I-SHKR and S-SHKR and explore their association with return of spontaneous circulation (ROSC) rates in dogs and cats undergoing cardiopulmonary resuscitation (CPR). This was a multi-institutional prospective case series from 2016-2021 retrospectively analyzed, that included eight university and eight private practice veterinary hospitals. 457 dogs and 170 cats with recorded cardiac arrest rhythm and event outcome reported in the Reassessment Campaign on Veterinary Resuscitation CPR registry. Logistic regression was used to evaluate association of animal, hospital, and arrest variables with I-SHKR and S-SHKR and with patient outcomes. Odds ratios (OR) were generated, and significance set at P < 0.05. Of 627 animals included, 28 (4%) v had I-SHKR. Odds for I-SHKR were significantly higher in animals with a metabolic cause of arrest (OR 7.61), that received lidocaine (OR 17.50) or amiodarone (OR 21.22), and significantly lower in animals experiencing arrest during daytime hours (OR 0.22), in the ICU (OR 0.27), ER (OR 0.13), out-of-hospital (OR 0.18), and in those that received epinephrine (OR 0.19). Of 599 initial non-shockable rhythms (I-NSHKR), 74 (12%) developed S-SHKR. Odds for S-SHKR were significantly higher in animals with higher body weight (OR 1.03), hemorrhage (OR 2.85) or intracranial (OR 3.73) cause of arrest, and that received lidocaine (OR 18.72), and significantly decreased in those arresting in ICU (OR 0.27), ER (OR 0.29), out-of-hospital (OR 0.38), and that received epinephrine (OR 0.09). Overall, 171 (27%) animals achieved ROSC, 81 (13%) sustained ROSC, and 15 (2%) survived. Neither I-SHKR nor S-SHKR were significantly associated with ROSC. As a conclusion, I-SHKR and S-SHKR occur infrequently in dogs and cats undergoing CPR and are not associated with increased ROSC rates.
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Details
- Title
- Prevalence and factors associated with initial and subsequent shockable cardiac arrest rhythms and their association with patient outcomes in dogs and cats undergoing cardiopulmonary resuscitation: a Recover registry study
- Creators
- Laura Vega
- Contributors
- Linda Gail Martin (Advisor)Sabrina Hoehne (Advisor)Lais De Matos Malavasi (Committee Member)
- Awarding Institution
- Washington State University
- Academic Unit
- Veterinary Medicine, College of
- Theses and Dissertations
- Master of Science (MS), Washington State University
- Publisher
- Washington State University
- Number of pages
- 56
- Identifiers
- 99901031340901842
- Language
- English
- Resource Type
- Thesis