Thesis
Role of Leukotriene Modifiers in the Treatment of Asthma
Washington State University
Master of Nursing (MN), Washington State University
05/2000
Handle:
https://hdl.handle.net/2376/3961
Abstract
Asthma is the most common respiratory disease encountered by nurse practitioners in clinical practice. There is no cure for asthma and it is not always controlled with existing therapies. Leukotrienes are recognized as the major causing factor in the pathology of asthma. Leukotrienes promote bronchoconstriction, mucus secretion, vascular leak and edema formation. Over the past decade a number of agents, known as leukotriene modifiers or antagonists, have been introduced and approved for the treatment of patients with asthma. Studies demonstrate the effectiveness of leukotreine antagonists in modifying bronchospasm with exercise, pulmonary reaction to aspirin in sensitive patients, and airway response to inhaled antigen. In patients with chronic asthma, leukotriene modifiers improve airflow obstruction, diminish asthma symptoms and decrease use of beta-agonists and inhaled corticosteroids. The goal of this paper is twofold: 1) to assist the nurse practitioner to make appropriate decisions about antileukotriene use; and 2) to delineate criteria used when selecting patients who will benefit from therapy with leukotriene modifiers.
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Details
- Title
- Role of Leukotriene Modifiers in the Treatment of Asthma
- Creators
- Krzysztof Szygorski
- Contributors
- Gail Synoground (Advisor)
- Awarding Institution
- Washington State University
- Academic Unit
- Research Projects, College of Nursing
- Theses and Dissertations
- Master of Nursing (MN), Washington State University
- Publisher
- Washington State University; Spokane, Washington
- Identifiers
- 99900591146201842
- Copyright
- http://creativecommons.org/licenses/by-nc-sa/3.0/us; Creative Commons Attribution-NonCommercial-ShareAlike 3.0 United States (CC BY-NC-SA 3.0 US)
- Language
- English
- Resource Type
- Thesis