Thesis
Temporal and spatial dependency of high frequency wave collisions in rat somatosensory cortex
Washington State University
Master of Science (MS), Washington State University
2008
Handle:
https://hdl.handle.net/2376/100092
Abstract
Multivibrissal sensory integration may be accomplished through the interaction of interference patterns from fast oscillatory (FO) spreading waves across cortical barrels; analogous to waves in water. We studied the interference patterns of FO occurring after paired whisker stimulation and examined the relative wave amplitudes under different whisker stimulus delays and directions. We observed both supralinear and sublinear FO integration that was sensitive to 0-5 ms time delays and to the sequential order in which whiskers were stimulated. The somatosensory evoked potential (SEP) measured between the two cortical columns was not significantly affected by these short delays. Since the maximal and minimal response occurred during delay times corresponding to a FO half period, we hypothesize that wave interference and collisions are responsible for modulating the final amplitude of the spreading wave. The maximum effect occurred between barrels of the same whisker row in the rostral to caudal direction but also occurred to a lesser extent between cortical barrels of the same whisker arc. These results suggest that FOs preferentially interfere in the rostral to caudal whisker direction, which may represent the natural flow of information as the rat whisks in its environment. FO spreading also occurred in other directions but produced less pronounced interference effects, probably related to differences in the organization of underlying circuitry and coupling.
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Details
- Title
- Temporal and spatial dependency of high frequency wave collisions in rat somatosensory cortex
- Creators
- Alexander Carvajal
- Contributors
- David M. Rector (Degree Supervisor)
- Awarding Institution
- Washington State University
- Academic Unit
- Integrative Physiology and Neuroscience, Department of
- Theses and Dissertations
- Master of Science (MS), Washington State University
- Publisher
- Washington State University; Pullman, Wash. :
- Identifiers
- 99900525089901842
- Language
- English
- Resource Type
- Thesis