Thesis
The effects of whey protein and soy protein in the prevention of exercise-induced oxidative stress and inflammatory damage in human athletes
Washington State University
Master of Science (MS), Washington State University
2009
Handle:
https://hdl.handle.net/2376/100560
Abstract
Back ground: During endurance athletic events, metabolic changes occur that are detrimental to physiological homeostasis. Inflammatory response during exercise occurs, potentially resulting in increased oxidative damage. Protein supplements from whey and soy may therefore play a role in alleviating oxidative damage and improve body composition and immune support. Objective: The objective of this study was to evaluate the effects of whey and soy protein isolate on oxidative stress, inflammatory damage, immune biomarkers, and body composition in female endurance athletes. Design: Healthy female endurance athletes (18-25 yr; n =33) were fed 40 g of whey or soy protein daily for 6 wk. Blood samples were collected on wk 0 and 6 for analysis of oxidative, inflammatory, and immune biomarkers. DXA scans were performed to determine body composition. Results: Whey protein intervention lowered (P< 0.05) plasma CRP concentrations after 6 wk of supplementation in female athletes compared to those who received soy protein. There was no corresponding change in circulating IL-1 and IL-6, suggesting that the anti-inflammatory action of whey protein is unlikely due to changes in these cytokines. In addition, whey but not soy protein decreased (P< 0.01) lipid peroxidation. In contrast, athletes given soy protein had lower plasma 8-OHdG (P< 0.07). Total bone mineral density (P< 0.05) and bone mineral composition (P< 0.06) were higher (P< 0.06) in subjects fed whey protein than those given soy protein. However, total bone mass (P< 0.06) and lean mass (P< 0.05) were higher in subjects given soy protein than those given whey protein. Conclusions: Both whey and soy protein supplements can be beneficial to athletes. Both protein supplements provide anti-oxidative action. Specifically, WPI increased bone mineral, decreased inflammation, lipid peroxidation, and body fat, while SPI decreased DNA damage and increased total and lean body mass.
Metrics
17 File views/ downloads
54 Record Views
Details
- Title
- The effects of whey protein and soy protein in the prevention of exercise-induced oxidative stress and inflammatory damage in human athletes
- Creators
- Myra K. Tara
- Contributors
- Boon P. Chew (Degree Supervisor)Jean Soon Park (Degree Supervisor)
- Awarding Institution
- Washington State University
- Academic Unit
- Food Science, School of
- Theses and Dissertations
- Master of Science (MS), Washington State University
- Publisher
- Washington State University; Pullman, Wash. :
- Identifiers
- 99900525142701842
- Language
- English
- Resource Type
- Thesis