Thesis
UTILITY OF CALCIUM PHOSPHORUS RATIO IN THE PREDICTION OF NEOPLASIA IN AZOTEMIC HYPERCALCEMIC DOGS
Washington State University
Master of Science (MS), Washington State University
01/2022
DOI:
https://doi.org/10.7273/000004467
Handle:
https://hdl.handle.net/2376/124669
Abstract
The objective of this retrospective study was to evaluate dogs with total hypercalcemia, azotemia, and normal serum phosphorus concentrations to determine if this constellation of laboratory abnormalities could predict neoplasia. A secondary aim was to determine if a calcium phosphorus ratio could be utilized to predict underlying neoplasia. A total of 129 dogs were included in the study. Seventy-three (56.6%) of the patients had presumed non-neoplastic disease and 56 (43.4%) had known neoplasia. Total hypercalcemia in this study confirmed previous associations of hypercalcemia with neoplasia, finding that in this population of dogs, the neoplastic group had a statistically significant higher total calcium that the non-neoplastic group. The other variables, azotemia and serum phosphorus, did not contribute significantly to the predication of neoplasia. A calcium phosphorus ratio has not been previously evaluated in veterinary medicine. For this study, an observation cutoff of 2.6 or greater was used for determining sensitivity and specificity between the neoplasia and non-neoplasia groups. The sensitivity and specificity of this ratio was low and thus makes it an unreliable tool to predict neoplasia in this specific study population.
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Details
- Title
- UTILITY OF CALCIUM PHOSPHORUS RATIO IN THE PREDICTION OF NEOPLASIA IN AZOTEMIC HYPERCALCEMIC DOGS
- Creators
- Kaylyn McDaniel
- Contributors
- Rance K Sellon (Advisor)Sarah C Guess (Committee Member)Jillian Haines (Committee Member)
- Awarding Institution
- Washington State University
- Academic Unit
- Veterinary Medicine, College of
- Theses and Dissertations
- Master of Science (MS), Washington State University
- Publisher
- Washington State University
- Number of pages
- 18
- Identifiers
- 99900882026401842
- Language
- English
- Resource Type
- Thesis