Journal article
A Divergent Cellular Role for the FUSED Kinase Family in the Plant-Specific Cytokinetic Phragmoplast
Current biology, Vol.15(23), pp.2107-2111
2005
Handle:
https://hdl.handle.net/2376/105487
PMID: 16332535
Abstract
The FUSED (FU) Ser/Thr protein kinase family has a key role in the hedgehog signaling pathway known to control cell proliferation and patterning in fruit flies and humans
[1, 2]. The genomes of
Arabidopsis thaliana and rice each encode a single
Fu ortholog, but their role is unknown. Here, we show that cytokinesis-defective mutants, which we named
two-in-one (
tio), result from mutations in
Arabidopsis Fu. Phenotypic analysis of
tio mutants reveals an essential role for TIO in conventional modes of cytokinesis in plant meristems and during male gametogenesis. TIO also has a key role in nonconventional modes of cytokinesis (cellularization) during female gametogenesis. We demonstrate that TIO is tightly localized to the midline of the nascent phragmoplast and remains associated with the expanding phragmoplast ring. These data reveal the evolution of a divergent role for the Fu kinase family as an essential phragmoplast-associated protein that functions in different cell type-specific modes of cytokinesis in plants.
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Details
- Title
- A Divergent Cellular Role for the FUSED Kinase Family in the Plant-Specific Cytokinetic Phragmoplast
- Creators
- Sung Aeong Oh - Department of Biology, University of Leicester, University Road, Leicester LE1 7RH, United KingdomAndrew Johnson - Department of Biology, University of Leicester, University Road, Leicester LE1 7RH, United KingdomAndrei Smertenko - The Integrative Cell Biology Laboratory, School of Biological and Biomedical Sciences, University of Durham, South Road, Durham DH1 3LE, United KingdomDaisy Rahman - Department of Biology, University of Leicester, University Road, Leicester LE1 7RH, United KingdomSoon Ki Park - Division of Plant Biosciences, Kyungpook National University, Daegu 702-701, South KoreaPatrick J Hussey - The Integrative Cell Biology Laboratory, School of Biological and Biomedical Sciences, University of Durham, South Road, Durham DH1 3LE, United KingdomDavid Twell - Department of Biology, University of Leicester, University Road, Leicester LE1 7RH, United Kingdom
- Publication Details
- Current biology, Vol.15(23), pp.2107-2111
- Academic Unit
- Institute of Biological Chemistry
- Publisher
- Elsevier Inc
- Number of pages
- 5
- Identifiers
- 99900546715501842
- Copyright
- Elsevier user license: used for Elsevier open archive, which makes the final published article from certain journals free to read after an embargo period.
- Language
- English
- Resource Type
- Journal article