Journal article
A concise [C+NC+CC] coupling-enabled synthesis of kaitocephalin
Chemical communications (Cambridge, England), Vol.50(38), pp.4908-4910
2014
Handle:
https://hdl.handle.net/2376/106031
PMID: 24691728
Abstract
A 15-step synthesis of the iGluR antagonist kaitocephalin from aspartic acid is reported. The linchpin pyrrolidine ring of the target molecule is efficiently assembled with in a single operation via an asymmetric [C+NC+CC] reaction.
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Details
- Title
- A concise [C+NC+CC] coupling-enabled synthesis of kaitocephalin
- Creators
- Philip Garner - Department of Chemistry, Washington State University, Pullman, USALaksiri Weerasinghe - Department of Chemistry, Washington State University, Pullman, USAIan Van Houten - Department of Chemistry, Washington State University, Pullman, USAJieyu Hu - Department of Chemistry, Washington State University, Pullman, USA
- Publication Details
- Chemical communications (Cambridge, England), Vol.50(38), pp.4908-4910
- Academic Unit
- Chemistry, Department of
- Identifiers
- 99900546947001842
- Language
- English
- Resource Type
- Journal article