Journal article
Ammonia-dependent differential regulation of the gene cluster that encodes ammonia monooxygenase in Nitrosococcus oceani ATCC 19707
Environmental microbiology, Vol.10(11), pp.3026-3035
11/2008
Handle:
https://hdl.handle.net/2376/104484
PMID: 18973622
Abstract
Molecular analysis of the ammonia monooxygenase-encoding gene cluster in Nitrosococcus oceani revealed that the amo genes are differentially expressed from three promoters dependent on the external ammonia concentration. Whereas a distal amoRCABD operon promoter, pC1, is active only in the presence of ammonia, identified proximal amoC (pC2) and amoA (pA) sigma-70-type promoters are constitutive. Promoter region pC2 also contains a consensus sequence for binding of RpoN, usually involved in nitrogen starvation response. Additional regulation of transcript stability by anti-termination and mRNA degradation are proposed and discussed.
Metrics
9 Record Views
Details
- Title
- Ammonia-dependent differential regulation of the gene cluster that encodes ammonia monooxygenase in Nitrosococcus oceani ATCC 19707
- Creators
- Amal F El Sheikh - Department of Biology, Evolutionary and Genomic Microbiology Laboratory, University fo Louisville, Louisville, KY, USAMartin G Klotz
- Publication Details
- Environmental microbiology, Vol.10(11), pp.3026-3035
- Academic Unit
- Molecular Biosciences, School of
- Publisher
- England
- Identifiers
- 99900546764901842
- Language
- English
- Resource Type
- Journal article