Journal article
Ammonium tetrathiomolybdate as a water-soluble and slow-release hydrogen sulfide donor
Bioorganic & medicinal chemistry letters, Vol.26(6), pp.1585-1588
03/15/2016
Handle:
https://hdl.handle.net/2376/108352
PMCID: PMC4775341
PMID: 26898812
Abstract
[Display omitted]
Ammonium tetrathiomolybdate (TTM) was found to be a slow hydrogen sulfide (H2S) releasing agent. Its H2S generation capability in aqueous solutions was confirmed by UV–vis and fluorescence assays. TTM also showed H2S-like cytoprotective effects in hydrogen peroxide (H2O2)-induced oxidative damage in HaCaT cells.
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Details
- Title
- Ammonium tetrathiomolybdate as a water-soluble and slow-release hydrogen sulfide donor
- Creators
- Shi Xu - Department of Chemistry, Washington State University, Pullman, WA 99164, United StatesChun-Tao Yang - Department of Physiology, Guangzhou Medical University, Guangzhou 511436, ChinaFu-Hui Meng - Department of Physiology, Guangzhou Medical University, Guangzhou 511436, ChinaArmando Pacheco - Department of Chemistry, Washington State University, Pullman, WA 99164, United StatesLi Chen - Department of Physiology, Guangzhou Medical University, Guangzhou 511436, ChinaMing Xian - Department of Chemistry, Washington State University, Pullman, WA 99164, United States
- Publication Details
- Bioorganic & medicinal chemistry letters, Vol.26(6), pp.1585-1588
- Academic Unit
- Chemistry, Department of
- Publisher
- Elsevier Ltd
- Identifiers
- 99900547426301842
- Language
- English
- Resource Type
- Journal article