An evaluation of evidence for the carcinogenic activity of bisphenol A

Ruth A Keri; Shuk-Mei Ho; Patricia A Hunt; Karen E Knudsen; Ana M Soto; Gail S Prins

doi:10.1016/j.reprotox.2007.06.008

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An evaluation of evidence for the carcinogenic activity of bisphenol A

Journal article

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An evaluation of evidence for the carcinogenic activity of bisphenol A

Ruth A Keri, Shuk-Mei Ho, Patricia A Hunt, Karen E Knudsen, Ana M Soto and Gail S Prins

Reproductive toxicology (Elmsford, N.Y.), Vol.24(2), pp.240-252

2007

DOI: https://doi.org/10.1016/j.reprotox.2007.06.008

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https://hdl.handle.net/2376/104410

PMCID: PMC2442886

PMID: 17706921

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https://doi.org/10.1016/j.reprotox.2007.06.008View

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Abstract

Bisphenol A

Estrogen receptor

Uterus

Breast

Mammary

Prostate

Cancer

The National Institutes of Health (NIEHS, NIDCR) and the United States Environmental Protection Agency convened an expert panel of scientists with experience in the field of environmental endocrine disruptors, particularly with knowledge and research on bisphenol A (BPA). Five subpanels were charged to review the published literature and previous reports in five specific areas and to compile a consensus report with recommendations. These were presented and discussed at an open forum entitled “Bisphenol A: An Expert Panel Examination of the Relevance of Ecological, In Vitro and Laboratory Animal Studies for Assessing Risks to Human Health” in Chapel Hill, NC on 28–30 November 2006. The present review consists of the consensus report on the evidence for a role of BPA in carcinogenesis, examining the available evidence in humans and animal models with recommendations for future areas of research.

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Title: An evaluation of evidence for the carcinogenic activity of bisphenol A
Creators: Ruth A Keri - Department of Pharmacology and Division of General Medical Sciences—Oncology, Case Western Reserve University, Cleveland, OH 44160, United States
Shuk-Mei Ho - Department of Environmental Health, University of Cincinnati, Cincinnati, OH 45267, United States
Patricia A Hunt - School of Molecular Biosciences, Washington State University, Pullman, WA 99164, United States
Karen E Knudsen - Department of Cell Biology, University of Cincinnati, Cincinnati, OH 45267, United States
Ana M Soto - Department of Anatomy and Cell Biology, Tufts University, Boston, MA 02111, United States
Gail S Prins - Department of Urology, University of Illinois at Chicago, M/C 955, 820 S. Wood, Chicago, IL 60612, United States
Publication Details: Reproductive toxicology (Elmsford, N.Y.), Vol.24(2), pp.240-252
Academic Unit: Molecular Biosciences, School of
Publisher: Elsevier Inc
Identifiers: 99900546889101842
Language: English
Resource Type: Journal article