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Ancestral dichlorodiphenyltrichloroethane (DDT) exposure promotes epigenetic transgenerational inheritance of obesity
Journal article   Open access  Peer reviewed

Ancestral dichlorodiphenyltrichloroethane (DDT) exposure promotes epigenetic transgenerational inheritance of obesity

Michael K Skinner, Mohan Manikkam, Rebecca Tracey, Carlos Guerrero-Bosagna, Muksitul Haque and Eric E Nilsson
BMC medicine, Vol.11(1), pp.228-228
10/23/2013
Handle:
https://hdl.handle.net/2376/107430
PMCID: PMC3853586
PMID: 24228800
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Ancestral dichlorodiphenyltrichloroethane (DDT) exposure 2.50 MBDownloadView
CC BY V4.0 Open Access
url
https://doi.org/10.1186/1741-7015-11-228View
Published (Version of record) Open

Abstract

Environmental epigenetics Epimutations Maternal transmission Obesity associated disease Disease etiology Epigenetics Metabolic Syndrome
Background: Ancestral environmental exposures to a variety of environmental factors and toxicants have been shown to promote the epigenetic transgenerational inheritance of adult onset disease. The present work examined the potential transgenerational actions of the insecticide dichlorodiphenyltrichloroethane (DDT) on obesity and associated disease.

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