Journal article
Assessing the impact of the NIH CTSA program on institutionally sponsored clinical trials
Clinical and translational science, Vol.6(3), pp.196-200
06/2013
Handle:
https://hdl.handle.net/2376/116577
PMCID: PMC3684971
PMID: 23751024
Abstract
To assess the impact of the NIH CTSA program on patient enrollment in clinical trials sponsored/collaborated by CTSA consortium institutions.
Using publicly available clinical trial data at ClinicalTrials.gov, we identify positive trend changes in the number of patients enrolled in clinical trials performed at CTSA consortium institutions over the years before and after their respective CTSA award dates. CTSA consortium institutions were matched with similar non-CTSA institutions.
As compared to matched non-CTSA institutions CTSA consortium sites noted an increase in patient enrollment after the CTSA awards. In particular, we detected a change-point, where a new enrollment trend emerged, 338 days after the CTSA award. No such trend was noted over the same period in the non-CTSA institutions.
Our analysis provides evidence that the NIH CTSA funding program made a positive impact on patient enrollment.
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Details
- Title
- Assessing the impact of the NIH CTSA program on institutionally sponsored clinical trials
- Creators
- Guodong Liu - Penn State College of Medicine, Public Health Sciences, Hershey, PA, USAGang ChenLawrence I SinowayArthur Berg
- Publication Details
- Clinical and translational science, Vol.6(3), pp.196-200
- Academic Unit
- Pharmaceutical Sciences, Department of
- Publisher
- United States
- Grant note
- UL1 TR000127 / NCATS NIH HHS
- Identifiers
- 99900547550701842
- Language
- English
- Resource Type
- Journal article