Characterization of N-glucuronidation of the lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in human liver: Importance of UDP-glucuronosyltransferase 1A4

Journal article

Peer reviewed

Doris WIENER, Daniel R DOERGE, Jia-Long FANG, Pramod UPADHYAYA and Philip LAZARUS

Drug metabolism and disposition, Vol.32(1), pp.72-79

2004

Handle:

https://hdl.handle.net/2376/116424

PMID: 14709623

Abstract

Biological and medical sciences

Toxicology

Medical sciences

Tobacco, tobacco smoking

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Title: Characterization of N-glucuronidation of the lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in human liver: Importance of UDP-glucuronosyltransferase 1A4
Creators: Doris WIENER - Cancer Epidemiology and Prevention Program, H. Lee Moffitt Cancer Center, Department of Interdisciplinary Oncology, University of South Florida, Tampa, Florida, United States
Daniel R DOERGE - Division of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, Arkansas, United States
Jia-Long FANG - Cancer Epidemiology and Prevention Program, H. Lee Moffitt Cancer Center, Department of Interdisciplinary Oncology, University of South Florida, Tampa, Florida, United States
Pramod UPADHYAYA - University of Minnesota Cancer Center, Minneapolis, Minnesota, United States
Philip LAZARUS - Cancer Epidemiology and Prevention Program, H. Lee Moffitt Cancer Center, Department of Interdisciplinary Oncology, University of South Florida, Tampa, Florida, United States
Publication Details: Drug metabolism and disposition, Vol.32(1), pp.72-79
Academic Unit: Pharmaceutical Sciences, Department of
Publisher: American Society for Pharmacology and Experimental Therapeutics; Bethesda, MD
Identifiers: 99900548398801842
Language: English
Resource Type: Journal article