Journal article
Cigarette, Cigar, and Pipe Smoking and the Risk of Head and Neck Cancers: Pooled Analysis in the International Head and Neck Cancer Epidemiology Consortium
American journal of epidemiology, Vol.178(5), pp.679-690
2013
Handle:
https://hdl.handle.net/2376/110695
PMCID: PMC3755640
PMID: 23817919
Abstract
Cigar and pipe smoking are considered risk factors for head and neck cancers, but the magnitude of effect estimates for these products has been imprecisely estimated. By using pooled data from the International Head and Neck Cancer Epidemiology (INHANCE) Consortium (comprising 13,935 cases and 18,691 controls in 19 studies from 1981 to 2007), we applied hierarchical logistic regression to more precisely estimate odds ratios and 95% confidence intervals for cigarette, cigar, and pipe smoking separately, compared with reference groups of those who had never smoked each single product. Odds ratios for cigar and pipe smoking were stratified by ever cigarette smoking. We also considered effect estimates of smoking a single product exclusively versus never having smoked any product (reference group). Among never cigarette smokers, the odds ratio for ever cigar smoking was 2.54 (95% confidence interval (CI): 1.93, 3.34), and the odds ratio for ever pipe smoking was 2.08 (95% CI: 1.55, 2.81). These odds ratios increased with increasing frequency and duration of smoking (P-trend <= 0.0001). Odds ratios for cigar and pipe smoking were not elevated among ever cigarette smokers. Head and neck cancer risk was elevated for those who reported exclusive cigar smoking (odds ratio = 3.49, 95% CI: 2.58, 4.73) or exclusive pipe smoking (odds ratio = 3.71, 95% CI: 2.59, 5.33). These results suggest that cigar and pipe smoking are independently associated with increased risk of head and neck cancers.
Metrics
12 Record Views
Details
- Title
- Cigarette, Cigar, and Pipe Smoking and the Risk of Head and Neck Cancers: Pooled Analysis in the International Head and Neck Cancer Epidemiology Consortium
- Creators
- Annah WYSS - Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United StatesMia HASHIBE - Department of Family and Preventive Medicine, School of Medicine, University of Utah, Salt Lake City, Utah, United StatesErich M STURGIS - Department of Head and Neck Surgery, Division of Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas, United StatesElaine SMITH - Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, Iowa, United StatesOxana SHANGINA - Department of Epidemiology and Prevention, Institute of Carcinogenesis, N. N. Blokhin Cancer Research Center, Moscow, Russian FederationStephen M SCHWARTZ - Department of Epidemiology, School of Public Health, University of Washington, and Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United StatesStimson SCHANTZ - Biostatistics and Epidemiology Service, Department of Otolaryngology, The New York Eye and Ear Infirmary, New York, New York, United StatesPeter RUDNAI - Department of Environmental Epidemiology, National Institute of Environmental Health, Budapest, HungaryMark P PURDUE - Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United StatesJose ELUF-NETO - Department of Preventive Medicine, Faculty of Medicine, University of São Paulo, São Paulo, BrazilJoshua MUSCAT - Department of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania, United StatesHal MORGENSTERN - Departments of Epidemiology and Environmental Health Sciences, School of Public Health and Comprehensive Cancer Center, University of Michigan, Ann Arbor, Michigan, United StatesShu-Chun CHUANG - Institute of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan, Province of ChinaPedro MICHALUART - Head and Neck Service, Faculty of Medicine, University of São Paulo, São Paulo, BrazilAna MENEZES - Federal University of Pelotas, Pelotas, BrazilElena MATOS - Angel H. Roffo Institute of Oncology, University of Buenos Aires, Buenos Aires, ArgentinaIoan Nicolae MATES - Carol Davila University of Medicine and Pharmacy, Bucharest, RomaniaJolanta LISSOWSKA - Department of Cancer Epidemiology and Prevention, The Maria Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology, Warsaw, PolandFabio LEVI - Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United StatesPhilip LAZARUS - Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United StatesCarlo LA VECCHIA - Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United StatesSergio KOIFMAN - Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United StatesRolando HERRERO - Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United StatesYuan-Chin Amy LEE - Department of Family and Preventive Medicine, School of Medicine, University of Utah, Salt Lake City, Utah, United StatesRichard B HAYES - Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United StatesSilvia FRANCESCHI - Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United StatesVictor WÜNSCH-FILHO - Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United StatesLeticia FERNANDEZ - Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United StatesEleonora FABIANOVA - Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United StatesAlexander W DAUDT - Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United StatesLuigino DAL MASO - Epidemiology and Biostatistics Unit, National Cancer Institute of Aviano, Aviano, ItalyMaria Paula CURADO - Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United StatesCHU CHU CHEN - Department of Epidemiology, School of Public Health, University of Washington, and Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United StatesXavier CASTELLSAGUE - Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United StatesZuo-Feng ZHANG - Department of Epidemiology, School of Public Health, University of California Los Angeles, Los Angeles, California, United StatesMarcos Brasilino DE CARVALHO - Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United StatesGabriella CADONI - Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United StatesStefania BOCCIA - Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United StatesPaul BRENNAN - Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United StatesPaolo BOFFETTA - Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United StatesAndrew F OLSHAN - Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United StatesGuo-Pei YU - Department of Otolaryngology, New York Medical College, New York, New York, United StatesDeborah M WINN - Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United StatesQINGYI QINGYI WEI - Department of Epidemiology, Division of Cancer Prevention and Population Sciences, University of Texas MD Anderson Cancer Center, Houston, Texas, United StatesRenato TALAMINI - Epidemiology and Biostatistics Unit, National Cancer Institute of Aviano, Aviano, ItalyNeonila SZESZENIA-DABROWSKA - Department of Epidemiology, Institute of Occupational Medicine, Lodz, Poland
- Publication Details
- American journal of epidemiology, Vol.178(5), pp.679-690
- Academic Unit
- Department of Pharmaceutical Sciences
- Publisher
- Oxford University Press; Cary, NC
- Number of pages
- 12
- Grant note
- T32ES007018 / National Institute of Environmental Health Sciences; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Environmental Health Sciences (NIEHS) T32CA009142 / National Cancer Institute; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI) T32-CA09330; R03 CA113157 / National Cancer Institute; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI) Union for International Cancer Control International Cancer Technology Transfer Fellowship
- Identifiers
- 99900547755901842
- Language
- Russian
- Resource Type
- Journal article