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Ciliary trafficking: CEP290 guards a gated community
Journal article   Open access  Peer reviewed

Ciliary trafficking: CEP290 guards a gated community

Ewelina Betleja and Douglas G Cole
Current biology, Vol.20(21), pp.R928-R931
11/09/2010
DOI: https://doi.org/10.1016/j.cub.2010.09.058
Handle:
https://hdl.handle.net/2376/110732
PMID: 21056833
url
https://doi.org/10.1016/j.cub.2010.09.058View
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Abstract

Plant Proteins - genetics Membrane Proteins - genetics Membrane Proteins - physiology Plant Proteins - physiology Chlamydomonas - genetics Cilia - ultrastructure Membrane Proteins - metabolism Plant Proteins - metabolism Chlamydomonas - metabolism Chlamydomonas - ultrastructure Cilia - metabolism Protein Transport - genetics
A recent study reveals that the large coiled-coil protein CEP290 is an integral component of the transition zone between the cell body and the cilium and functions as a gatekeeper to regulate trafficking of ciliary proteins.

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