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Circadian variation of nitric oxide synthase activity and cytosolic protein levels in rat brain
Journal article   Peer reviewed

Circadian variation of nitric oxide synthase activity and cytosolic protein levels in rat brain

Nancy A Ayers, Levente Kapás and James M Krueger
Brain research, Vol.707(1), pp.127-130
1996
Handle:
https://hdl.handle.net/2376/109218
PMID: 8866722

Abstract

Sleep Protein level Rat Nitric oxide Central nervous system Nitric oxide synthase Circadian rhythm Hypothalamus
The circadian variation of nitric oxide synthase (NOS) activity and cytosolic protein content in the cerebellum, brainstem, hypothalamus, hippocampus, and the remainder of the brain were studied in rats. Both NOS activity and cytosolic protein concentrations were the highest during the dark period and lowest in the light period. Hypothalamic NOS activity exhibited the most pronounced change in activity with time increasing by ∼ 120% from mid-light to mid-dark.

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