- Title
- Comparison between cytochrome P450 (CYP) content and relative activity approaches to scaling from cdna-expressed cyps to human liver microsomes : Ratios of accessory proteins as sources of discrepancies between the approaches
- Creators
- Karthik VENKATAKRISHNAN - Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine and the Division of Clinical Pharmacology, New England Medical Center, Boston, Massachusetts, United StatesLisa L VON MOLTKE - Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine and the Division of Clinical Pharmacology, New England Medical Center, Boston, Massachusetts, United StatesMichael H COURT - Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine and the Division of Clinical Pharmacology, New England Medical Center, Boston, Massachusetts, United StatesJerold S HARMATZ - Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine and the Division of Clinical Pharmacology, New England Medical Center, Boston, Massachusetts, United StatesCharles L CRESPI - Gentest Corporation, Woburn, Massachusetts, United StatesDavid J GREENBLATT - Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine and the Division of Clinical Pharmacology, New England Medical Center, Boston, Massachusetts, United States
- Publication Details
- Drug metabolism and disposition, Vol.28(12), pp.1493-1504
- Academic Unit
- Veterinary Clinical Sciences, Department of
- Publisher
- American Society for Pharmacology and Experimental Therapeutics; Bethesda, MD
- Identifiers
- 99900547540601842
- Language
- English
- Resource Type
- Journal article
Journal article
Comparison between cytochrome P450 (CYP) content and relative activity approaches to scaling from cdna-expressed cyps to human liver microsomes : Ratios of accessory proteins as sources of discrepancies between the approaches
Drug metabolism and disposition, Vol.28(12), pp.1493-1504
2000
Handle:
https://hdl.handle.net/2376/116335
PMID: 11095589
Abstract
Metrics
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