Journal article
Competitive binding analysis of monoclonal antibodies reactive with porcine alveolar macrophages using anti-CD14 and anti-CD18
Veterinary immunology and immunopathology, Vol.43(1), pp.273-278
1994
Handle:
https://hdl.handle.net/2376/109692
PMID: 7531910
Abstract
Four monoclonal antibodies (mAb) from the myeloid subset panel of the First International Swine CD Workshop (74-22-15, DH59B, PM16-6, and MUC21A) were analyzed using competitive inhibition studies with anti-human CD14 (My4) and anti-human/anti-porcine CD18 (MHM23) on porcine alveolar macrophages. Results suggested that none of the mAb tested recognized CD14 or CD18 on porcine alveolar macrophages. Additionally, the cross-reactivity of My4 with porcine alveolar macrophages was established.
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Details
- Title
- Competitive binding analysis of monoclonal antibodies reactive with porcine alveolar macrophages using anti-CD14 and anti-CD18
- Creators
- T Kielian - Department of Anatomy and Physiology, Kansas State University, Manhattan, KS 66506, USAD.S McVey - Department of Pathology and Microbiology, Kansas State University, Manhattan, KS 66506, USAW.C Davis - Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164, USAY.B Kim - Department of Microbiology and Immunology, University Health Sciences, The Chicago Medical School, N. Chicago, IL 60064, USAF Blecha - Department of Anatomy and Physiology, Kansas State University, Manhattan, KS 66506, USA
- Publication Details
- Veterinary immunology and immunopathology, Vol.43(1), pp.273-278
- Academic Unit
- Veterinary Microbiology and Pathology, Department of
- Publisher
- Elsevier B.V
- Identifiers
- 99900547285901842
- Language
- English
- Resource Type
- Journal article