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Contact Angle Changes Induced by Immunocomplex Formation
Journal article   Open access

Contact Angle Changes Induced by Immunocomplex Formation

Jong-Hoon Kim, Amy Q Shen, Kyong-Hoon Lee, Gerard A Cangelosi and Jae-Hyun Chung
Analyst (London), Vol.139(6), pp.1340-1344
03/21/2014
Handle:
https://hdl.handle.net/2376/108927
PMCID: PMC3977604
PMID: 24482797
url
https://doi.org/10.1039/c3an02189kView
Published (Version of record) Open

Abstract

Immunoassays analyzing interactions between antigens and antibodies can be affected by capillary action together with binding affinity. This paper studies contact-angle changes of bacterial suspensions on antibody immobilized surfaces. The capillary action and the dried pattern of the cell suspensions are analyzed and correlated with specific- and nonspecific bindings between bacteria and antibodies.

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