Journal article
Correlation between geographic distance and genetic similarity in an international collection of bovine faecal Escherichia coli O157[ratio ]H7 isolates
Epidemiology and infection, Vol.131(2), pp.923-930
10/2003
Handle:
https://hdl.handle.net/2376/108697
PMCID: PMC2870037
PMID: 14596534
Abstract
Evidence from epidemiological and molecular studies of bovine Escherichia coli O157[ratio ]H7 suggests that strains are frequently transmitted across wide geographic distances. To test this hypothesis, we compared the geographic and genetic distance of a set of international bovine Escherichia coli O157[ratio ]H7 isolates using the Mantel correlation. For a measure of genetic relatedness, pulsed-field gel electrophoresis of six different restriction enzyme digests was used to generate an average Dice similarity coefficient for each isolate pair. Geographic distance was calculated using latitude and longitude data for isolate source locations. The Mantel correlation between genetic similarity and the logarithm of geographic distance in kilometers was −0·21 (P<0·001). The low magnitude of the Mantel correlation indicates that transmission over long distances is common. The occurrence of isolates from different continents on the same cluster of the dendrogram also supports the idea that Escherichia coli O157[ratio ]H7 strains can be transferred with considerable frequency over global distances.
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Details
- Title
- Correlation between geographic distance and genetic similarity in an international collection of bovine faecal Escherichia coli O157[ratio ]H7 isolates
- Creators
- M. A DAVIS - Field Disease Investigation Unit, Department of Veterinary Clinical Sciences, Washington State University, Pullman, WA 99164, USAD. D HANCOCK - Field Disease Investigation Unit, Department of Veterinary Clinical Sciences, Washington State University, Pullman, WA 99164, USAT. E BESSER - Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164, USAD. H RICE - Field Disease Investigation Unit, Department of Veterinary Clinical Sciences, Washington State University, Pullman, WA 99164, USAC. J HOVDE - Department of Microbiology, Molecular Biology and Biochemistry, University of Idaho, Moscow, ID 83844, USAR DIGIACOMO - Division of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, WA 98195, USAM SAMADPOUR - Department of Environmental Health, School of Public Health and Community Medicine, University of Washington, Seattle, WA 98195, USAD. R CALL - Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164, USA
- Publication Details
- Epidemiology and infection, Vol.131(2), pp.923-930
- Academic Unit
- Veterinary Clinical Sciences, Department of; Veterinary Microbiology and Pathology, Department of; Paul G. Allen School for Global Animal Health
- Publisher
- Cambridge University Press; Cambridge, UK
- Number of pages
- 8
- Identifiers
- 99900547757401842
- Language
- English
- Resource Type
- Journal article