Journal article
Cross-reactivity of workshop antibodies with cells from domestic and wild ruminants
Veterinary immunology and immunopathology, Vol.39(1-3), pp.283-290
11/1993
Handle:
https://hdl.handle.net/2376/117957
PMID: 8310653
Abstract
Reactivities of the monoclonal antibodies (mAbs) from the workshop panel with cells from cattle, sheep, goats, Cape buffalo (Syncerus caffer) and waterbuck (Kobus defassa) were tested. One hundred and sixty-nine mAbs reacted with bovine cells and 111 with sheep cells; 86 were shown to react with goat cells, 71 with buffalo cells and 70 with waterbuck cells. Some mAbs cross-reacted with all five ruminants tested, and are likely to react with epitopes that are conserved in other ruminant species. Such mAbs will obviate the need to produce mAbs panels to leukocyte antigens of other ruminants.
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Details
- Title
- Cross-reactivity of workshop antibodies with cells from domestic and wild ruminants
- Creators
- J Naessens - International Laboratory for Research on Animal Diseases, Nairobi, KenyaR O OlubayoW C DavisJ Hopkins
- Publication Details
- Veterinary immunology and immunopathology, Vol.39(1-3), pp.283-290
- Academic Unit
- Veterinary Microbiology and Pathology, Department of
- Publisher
- Netherlands
- Identifiers
- 99900547966801842
- Language
- English
- Resource Type
- Journal article