Journal article
Cyclic rickettsemia during persistent Anaplasma marginale infection of cattle
Infection and immunity, Vol.58(4), pp.1117-1119
04/1990
Handle:
https://hdl.handle.net/2376/109045
PMCID: PMC258591
PMID: 2318532
Abstract
Submicroscopic levels of Anaplasma marginale rickettsemia in persistently infected cattle were determined by using nucleic acid hybridization. Within individuals, the rickettsemia levels steadily increased from less than 10(4) infected erythrocytes per ml to a peak of more than 10(6) infected erythrocytes per ml and then rapidly declined. This logarithmic variation parallels the variation of the rickettsemia level seen in acute infection and suggests that cyclic emergence of antigenic variants is a mechanism of rickettsial persistence.
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Details
- Title
- Cyclic rickettsemia during persistent Anaplasma marginale infection of cattle
- Creators
- S T Kieser - Department of Veterinary Microbiology and Pathology, U.S. Department of Agriculture, Pullman, WashingtonI S Eriks - Department of Veterinary Microbiology and Pathology, U.S. Department of Agriculture, Pullman, WashingtonG H Palmer - Department of Veterinary Microbiology and Pathology, U.S. Department of Agriculture, Pullman, Washington
- Publication Details
- Infection and immunity, Vol.58(4), pp.1117-1119
- Identifiers
- 99900547141001842
- Language
- English
- Resource Type
- Journal article