Journal article
Cytogenetic evaluation of four canine mast cell tumors
Cancer genetics and cytogenetics, Vol.53(1), pp.105-112
1991
Handle:
https://hdl.handle.net/2376/117406
PMID: 1903670
Abstract
We evaluated four canine cutaneous mast cell tumors cytogenetically. All four tumors contained both hypodiploid and hyperdiploid cells, an increase in the number of metacentric chromosomes, exchange configurations, and cells showing loss of an X chromosome. All tumors contained metaphases with chromosome gaps and breaks at frequencies greater than observed spontaneous chromosome breaks in normal cultured canine peripheral blood lymphocytes. Three of the four tumors had a normal modal chromosome number of 78. The fourth tumor had a modal chromosome number of 93, which represented 15% of the cells evaluated from this tumor.
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Details
- Title
- Cytogenetic evaluation of four canine mast cell tumors
- Creators
- Diana M Stone - Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington, USAPeter B Jacky - Department of Pathology/Cytogenetics, Kaiser Permanente Northwest Portland, Oregon, USADavid J Prieur - Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington, USA
- Publication Details
- Cancer genetics and cytogenetics, Vol.53(1), pp.105-112
- Academic Unit
- Veterinary Microbiology and Pathology, Department of
- Publisher
- Elsevier Inc
- Identifiers
- 99900548454801842
- Language
- English
- Resource Type
- Journal article