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Development and Characterization of an Equine Infectious Anemia Virus Env-Pseudotyped Reporter Virus
Journal article   Open access  Peer reviewed

Development and Characterization of an Equine Infectious Anemia Virus Env-Pseudotyped Reporter Virus

R. L Tallmadge, M. A Brindley, J Salmans, R. H Mealey, W Maury and S Carpenter
Clinical and vaccine immunology, Vol.15(7), pp.1138-1140
07/2008
Handle:
https://hdl.handle.net/2376/108974
PMCID: PMC2446648
PMID: 18448619
url
https://doi.org/10.1128/CVI.00088-08View
Published (Version of record) Open

Abstract

Vaccine Research
We developed a replication-defective reporter virus pseudotyped with the envelope glycoprotein of equine infectious anemia virus (EIAV). The in vitro host range and neutralization phenotype of EIAV Env-pseudotyped virus were similar to those of replication-competent virus. An EIAV Env pseudovirus will improve antigenic characterization of viral variants and evaluation of lentivirus vaccines.

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