Diversity in nucleotide binding site-leucine-rich repeat genes in cereals

Jianfa Bai; Lourdes A Pennill; Jianchang Ning; Se Weon Lee; Jegadeesan Ramalingam; Craig A Webb; Bingyu Zhao; Qing Sun; James C Nelson; Jan E Leach; Scot H Hulbert

doi:10.1101/gr.454902

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Diversity in nucleotide binding site-leucine-rich repeat genes in cereals

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Diversity in nucleotide binding site-leucine-rich repeat genes in cereals

Jianfa Bai, Lourdes A Pennill, Jianchang Ning, Se Weon Lee, Jegadeesan Ramalingam, Craig A Webb, Bingyu Zhao, Qing Sun, James C Nelson, Jan E Leach, …

Genome research, Vol.12(12), pp.1871-1884

12/2002

DOI: https://doi.org/10.1101/gr.454902

Handle:

https://hdl.handle.net/2376/112323

PMCID: PMC187567

PMID: 12466291

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Abstract

Consensus Sequence

Multigene Family - genetics

Amino Acid Sequence

Introns - genetics

Molecular Sequence Data

Nucleotides - genetics

Repetitive Sequences, Amino Acid - genetics

Gene Dosage

Protein Structure, Tertiary - genetics

Binding Sites - genetics

Phylogeny

Nucleotides - metabolism

Open Reading Frames - genetics

Sequence Homology, Nucleic Acid

Proteins - genetics

Edible Grain - genetics

Oryza - genetics

Genes, Plant - genetics

DNA Probes - genetics

Plant Diseases - genetics

Genetic Variation - genetics

Leucine - genetics

The diversity of the largest group of plant disease resistance genes, the nucleotide binding site-leucine-rich repeat (NBS-LRR) genes, was examined in cereals following polymerase chain reaction (PCR) cloning and database mining. NBS-LRR genes in rice are a large and diverse class with more than 600 genes, at least three to four times the complement of Arabidopsis. Most occur in small families containing one or a few cross-hybridizing members. Unlike in Arabidopsis and other dicots, the class of NBS-LRR genes coding for a Toll and mammalian interleukin-1 receptor (TIR) domain were not amplified during the evolution of the cereals. Genes coding for TIR domains are present in the rice genome, but have diverged from the NBS-LRR genes. Most cereal genes are similar in structure to the members of the non-TIR class of dicots, although many do not code for a coiled-coil domain in their amino termini. One unique class of cereal genes, with ~50 members, codes for proteins similar to the N-termini and NBS domains of resistance genes but does not code for LRR domains. The resistance gene repertoire of grasses has changed from that of dicots in their independent evolution since the two groups diverged. It is not clear whether this reflects a difference in downstream defense signaling pathways.

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Title: Diversity in nucleotide binding site-leucine-rich repeat genes in cereals
Creators: Jianfa Bai - Department of Plant Pathology, Kansas State University, Manhattan, Kansas 66506-5502, USA
Lourdes A Pennill
Jianchang Ning
Se Weon Lee
Jegadeesan Ramalingam
Craig A Webb
Bingyu Zhao
Qing Sun
James C Nelson
Jan E Leach
Scot H Hulbert
Publication Details: Genome research, Vol.12(12), pp.1871-1884
Academic Unit: Plant Pathology, Department of
Publisher: United States
Identifiers: 99900548578701842
Language: English
Resource Type: Journal article