Journal article
Effect of dietary restriction on cell-mediated immune responses in cattle infected with Mycobacterium bovis
Veterinary immunology and immunopathology, Vol.49(4), pp.307-320
1996
Handle:
https://hdl.handle.net/2376/114776
PMID: 8677633
Abstract
Nine
M. bovis-infected cattle on a diet deficent in both protein and energy for 133 days lost approximately 17% of their original body weight. However, dietary restriction did not result in any significant reduction in skin sensitivity to PPD, in vitro production of IFN-γ or lymphocyte blastogenesis. The numbers of circulating BoCD4
+ cells and B cells were similar in both the malnourished and the control cattle. However, significantly lower numbers (
P < 0.01) of circulating BoCD2
+ cells, BoCD8
+ cells, WC1
+ γδ T cells and ACT2
+ cells were found in the malnourished cattle. With the exception of inorganic phosphate, the changes in plasma biochemical parameters, were unremarkable.
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Details
- Title
- Effect of dietary restriction on cell-mediated immune responses in cattle infected with Mycobacterium bovis
- Creators
- Michael L Doherty - Faculty of Veterinary Medicine, University College Dublin, Ballsbridge, Dublin 4, IrelandMichael L Monaghan - Faculty of Veterinary Medicine, University College Dublin, Ballsbridge, Dublin 4, IrelandHugh F Bassett - Faculty of Veterinary Medicine, University College Dublin, Ballsbridge, Dublin 4, IrelandPatrick J Quinn - Faculty of Veterinary Medicine, University College Dublin, Ballsbridge, Dublin 4, IrelandWilliam C Davis - Department of Veterinary Microbiology and Pathology and Animal Health Research Center, Washington State University, Pullman, WA 99164, USA
- Publication Details
- Veterinary immunology and immunopathology, Vol.49(4), pp.307-320
- Academic Unit
- Veterinary Microbiology and Pathology, Department of
- Publisher
- Elsevier B.V
- Identifiers
- 99900547314101842
- Language
- English
- Resource Type
- Journal article