Journal article
Effect of hypophysectomy, replacement therapy with ovine prolactin, and cortisol and triiodothyronine treatment on prolactin receptors of the tilapia ( Oreochromis mossambicus)
General and comparative endocrinology, Vol.77(3), pp.378-385
1990
Handle:
https://hdl.handle.net/2376/109373
PMID: 2338218
Abstract
The effects of hypophysectomy and subsequent replacement therapy with ovine prolactin (oPRL) on specific binding of
25I-oPRL to gill, kidney, and liver membranes of male tilapia were examined. The possible control of prolactin receptors by cortisol (F) and triiodothyronine (T
3) was also studied using intact animals. In gill and kidney, hypophysectomy resulted in a significant decrease in specific binding that was partially restored (threefold increase) by three injections of oPRL, suggesting a role of the pituitary in the control of prolactin receptors. However, removal of the pituitary and replacement therapy with oPRL had no effect on binding by liver membranes. Cortisol and T
3 treatment, alone or in combination, did not significantly affect prolactin binding by any of the tissues tested.
Metrics
6 Record Views
Details
- Title
- Effect of hypophysectomy, replacement therapy with ovine prolactin, and cortisol and triiodothyronine treatment on prolactin receptors of the tilapia ( Oreochromis mossambicus)
- Creators
- Silvia DauderGraham YoungHoward A Bern
- Publication Details
- General and comparative endocrinology, Vol.77(3), pp.378-385
- Academic Unit
- UNKNOWN
- Publisher
- Elsevier Inc
- Identifiers
- 99900547705701842
- Language
- English
- Resource Type
- Journal article